Hi Ed, I admin a couple of mid-size WP multisites and a couple of smaller CBox ones.
I am running both Multisite Enhancements and Multisite Plugin Manager on our two mid-size servers. They seem to function just fine. There was one small issue with Multisite Enhancements involving favicons. If I recall it was initially sorted with some developer code that turned the feature off and/or/possibly with some patch code on the github for the plugin.
The main thing I find useful about Multisite Enhancements is that it tells you which subsites are using a theme or plugin. (column in the admin themes/plugin columns).
I use the Multisite Plugin Manager for a few purposes:
-keeping administrator/dangerous/security risk plugins out of the hands of individual users (Query Monitor, anything that writes custom code (be it JS, PHP or CSS) into pages, or advanced plugins that might require special oversight)
-this also leaves users with a less overwhelming plugin list
-we also use it for soft deprecation of plugins. As you know plugins/themes are a source of technical debt in the WordPress realm. The Plugin Manager has a functionality where if you turn a plugin off for general use it will remain active on subsites where it is already active but will disappear from the list once deactivated.
Both of these plugins come in handy for soft deprecation. When we are wanting to get rid of a plugin or theme ME gives us a small list of blog owners we need to contact. We generally give them a couple of weeks to make other arrangements and typically I try to find something that replaces the functionality. (For older servers it will often be the Gutenberg Block editor that replaces plugin/theme functionality.) I won’t rant about themes that contain code that belongs in plugin.
In any event, both of these plugins are still useful imho.